ABSOLUTELY YES! Pearls are VERY appropriate for the workplace because they are polished and sophisticated.
When looking to wear peals in the office, you have to be very conscious that they are not distracting and overwhelming so you should opt for pearl pieces that are simple. Simplicity is key when it comes to clothing and accessories at the workplace. You should never go to an office with the mind state of making it your runway.
Although you can look chic, you have to keep in mind that you are there to work not to show off your designer tags.
Here are some pieces that would look great for the office!